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What One Workflow Family Supports Today

A workflow family earns a serious public sentence only when its benchmark, runtime, grounding, recommendation, and consequence records form an inspectable chain. A convenient demonstration is not enough: an outside reviewer must be able to challenge the chain end to end without relying on maintainer memory.

The Minimum Family Packet

For this repository, one workflow family only earns a serious sentence when it has all of the following:

  • one flagship public benchmark package
  • one companion pressure package that tests adjacent transfer or stress
  • one explicit runtime lane with rerun or replay proof
  • one claim-grounding and contradiction route
  • one recommendation-pressure route
  • one downstream consequence or refusal route

If one of those pieces is missing, the family may still be useful, but the sentence has to narrow.

flowchart LR
    primary["flagship benchmark"] --> runtime["declared runtime lane"]
    companion["companion pressure package"] --> runtime
    runtime --> grounding["support and contradiction"]
    grounding --> recommendation["recommendation pressure"]
    recommendation --> consequence["consequence or refusal"]
    consequence --> sentence["bounded family sentence"]
    missing["missing or failed contract"] -.-> narrow["narrow or withhold the sentence"]
    primary -. missing .-> missing
    companion -. missing .-> missing
    runtime -. missing .-> missing
    grounding -. missing .-> missing
    recommendation -. missing .-> missing
    consequence -. missing .-> missing

Why DDA Still Works As The Clearest Example

DDA remains the best first family because its packet is easy to inspect as one bounded chain:

  • a flagship benchmark package
  • a companion cross-engine pressure package
  • a real import-backed runtime review lane
  • grounded scientific and comparator pressure
  • recommendation challenge and downgrade routes
  • consequence and follow-up boundaries

It is not the strongest family in every dimension, but it remains the clearest reader-first example of the full pattern.

What This Means In Practice

One serious family packet does not mean:

  • broad proteomics coverage
  • repository-wide readiness
  • decision-grade downstream authority

It means something narrower and still important:

one family can now be challenged from public evidence root to downstream consequence through tracked owner surfaces.

Current Family Reading

family current family packet status main reason the sentence still narrows
dda review_grade_bounded runtime remains import_only; external engines and parameters bound parity
dia outsider_auditable_bounded chromatogram-native replay, library completeness, and absent-peptide consequences remain bounded
lfq outsider_auditable_bounded cohort transfer and external quantitative truth beyond repeatability remain bounded
ptm outsider_auditable_bounded localization evidence is stronger than function, occupancy, and regulatory consequence evidence
targeted outsider_auditable_bounded vendor parity, calibration transfer, matrix interference, and assay burden remain bounded
multiplex internal_support_only companion pressure exposes fragile transfer; outsider review and laboratory consequence are incomplete

Strongest Companion Routes

Authority Boundary

A complete packet authorizes only the bounded sentence for that workflow family. It does not authorize repository-wide readiness, transfer evidence to another family, or turn analytical support into decision-grade authority. The family status and capability limits remain the controlling public records.